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It is well known that adductor muscle contraction plays an important role in scallop movement. However little is known how the muscle elicits the contraction. In the present report, we demonstrated the mechanisms of contraction and Ca^(2+)-dependency in scallop smooth adductor muscle. The experiments were performed with modified sea water at 15℃ and pH 7.8. High KCl, which Induces a depolarization of membrane potential, evoked a sustained increase in muscle contraction, in a dose-dependent manner. In the fluorescent dye, fura-PE3/AM, loaded scallop smooth adductor muscle, 200 mM high KCl elicited [Ca^(2+)],. The contraction induced by 200 mM KCl was inhibited by both 100μM verapamil, a L-type Ca^(2+) channel Mocker, and 16 mM EGTA. From these results, it is suggested that Ca^(2+) influx involves in the high KCl-induced contraction of scallop smooth adductor muscle.
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